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Understanding the ‘Quad-demic’: What You Need to Know About Rising Illnesses

Understanding the ‘Quad-demic’: What You Need to Know About Rising Illnesses
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  • PublishedJanuary 16, 2025

As cases of influenza, RSV, COVID-19, and norovirus surge across the United States, concerns about a so-called “quad-demic” have emerged, People reports.

The increase in these four viruses is leading to heightened vigilance, as each illness can result in hospitalization or, in some cases, be fatal. Here’s a breakdown of these illnesses, their impacts, and steps you can take to stay safe.

Influenza

The U.S. Centers for Disease Control and Prevention (CDC) has reported elevated levels of influenza activity, with 9.1 million illnesses, 110,000 hospitalizations, and 4,700 deaths attributed to the flu this season. Among those fatalities, 16 were children. States like Tennessee, Louisiana, Oregon, and New Mexico are experiencing the highest levels of flu activity.

Dr. Mandy K. Cohen, CDC Director, emphasizes the importance of vaccination to prevent severe illness. Treatment for the flu is generally supportive, but high-risk individuals—such as pregnant people, the elderly, and those with asthma—may be prescribed antiviral medications like Tamiflu.

Respiratory Syncytial Virus (RSV)

RSV, which causes respiratory distress, especially in young children, is also spreading at “very high” levels. This virus causes symptoms such as a runny nose, fever, and wheezing, which may worsen around days 3 to 5 of illness. For infants and young children, RSV can result in bronchiolitis, an inflammation of the smaller airways in the lungs. While there is an RSV vaccine for high-risk adults over 60 and for infants, treatment is mostly supportive, and severe cases may require hospitalization.

COVID-19

Although COVID-19 is no longer circulating at the pandemic levels of previous years, it is still causing a slight increase in hospitalizations. The virus has mutated, and immunity from prior infection or vaccination can diminish over time. The CDC recommends updated protection, and antiviral treatments are available for those at higher risk of severe illness. Mild cases can be managed at home, with individuals advised to isolate until 24 hours after symptoms improve.

Norovirus

Cases of norovirus, a highly contagious gastrointestinal illness, have also surged, with the CDC reporting 91 outbreaks recently. Unlike the other viruses, there is no vaccine for norovirus, and it is primarily spread through contaminated food, water, or contact with infected bodily fluids. The CDC advises thorough handwashing and careful food handling to avoid infection. Symptoms include nausea, vomiting, diarrhea, and stomach cramps, and while norovirus is generally self-limiting, its highly contagious nature can lead to widespread outbreaks.

As these viruses continue to spread, public health officials stress the importance of vaccination where available, regular handwashing, and staying home when sick to limit the spread of these illnesses. Though the rise in cases is concerning, these preventive measures can help reduce your risk of contracting or spreading the viruses.

By staying informed and taking appropriate precautions, individuals can help protect themselves and their communities from the ongoing “quad-demic” of respiratory and gastrointestinal viruses.

Joe Yans

Joe Yans is a 25-year-old journalist and interviewer based in Cheyenne, Wyoming. As a local news correspondent and an opinion section interviewer for Wyoming Star, Joe has covered a wide range of critical topics, including the Israel-Palestine war, the Russia-Ukraine conflict, the 2024 U.S. presidential election, and the 2025 LA wildfires. Beyond reporting, Joe has conducted in-depth interviews with prominent scholars from top US and international universities, bringing expert perspectives to complex global and domestic issues.